PHRM 4120 - Assay Design (4)
Prerequisites: CHEM 4500 /CHEM 4520 – Biochemistry & Lab, or with the consent of the instructor. This course teaches the skills needed for employment in a research and development entity in the pharmaceutical and biotechnology industries. There will be an overview of the drug discovery process followed by detailed review of assay methods applicable to early phase small-molecule discovery and upstream biologics development. Students will become familiar with different assays employed in the industries as screening tools and learn how to choose relevant assays to determine desired endpoints. Detailed review of protocols to enable, develop, and validate robust assays for target screening, potency and efficacy determinations, selectivity, and specificity will be presented.
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