PHRM 4110 - Bioprocessing and Cell Culture Lecture (3)
Prerequisites: BIOL 2200 - Molecular Biology of Cells I (3) or consent of the instructor. This course teaches the skills needed to work as a scientist in biotechnology production. Students will grow and monitor bacterial and mammalian cells on a laboratory scale that emulates the large-scale production used in industry. Students will become familiar with the cleaning, sterilization, aseptic inoculation, and operation and monitoring of fermenters and bioreactors. Students will then recover and purify proteins produced by those cell cultures using centrifugation, ultra-filtration, and chromatography techniques. The course emphasizes the use of current Good Manufacturing Practices (cGMP), and students gain experience following standard operating procedures.
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