May 05, 2024  
2019-2020 Graduate School Course Catalog 
    
2019-2020 Graduate School Course Catalog [ARCHIVED CATALOG]

PHRM 5160 - Physical Biochemistry (3)


Prerequisites: Physical Chemistry, Biochemistry or with the consent of the instructor. This course applies the concepts of physical chemistry to biological systems. Topics covered include the forces governing protein and nucleic acid stability and topology, the thermodynamics of protein folding and protein-ligand interactions, enzyme kinetics, and the physical basis for methods for protein purification, for probing protein-ligand interactions, and for the determination of macromolecular structure. Emphasis will be given to topics relevant to the drug discovery process.


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