Mar 28, 2024  
Graduate School Course Catalog 2018-2019 
    
Graduate School Course Catalog 2018-2019 [ARCHIVED CATALOG]

PHRM 5230 - The Organic Chemistry of Drug Design and Drug Action (3)


Prerequisites: Organic Chemistry, Biochemistry or with the consent of the instructor. The success in drug design is dependent on insights and advances from the combined use of chemical and biological research.  The goal of this course will be to educate students in drug design and drug action.  This course will provide students the opportunity to become learn why drug-receptor interactions are important to drug efficacy, understand the mechanisms of drug chemistry, identify the pharmacophore of a target structure, examine structure modification to increase potency (SAR), become familiar with computational approaches used in the drug design and learn how medicinal chemists try to solve problems of metabolic destruction of drugs.


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