Dec 09, 2019  
Graduate School Course Catalog 2018-2019 
    
Graduate School Course Catalog 2018-2019 [ARCHIVED CATALOG]

PHRG 5220 - Chemical Library Design (3)


Prerequisites: Organic Chemistry, Biochemistry or with the consent of the instructor. This course will provide students the opportunity to become familiar with techniques used in chemical library design and synthesis such as: computer aided library design, solution and solid phase rapid parallel synthesis (RPS) and parallel purification. Upon completion of this course, students will be able to use the literature or data from a high throughput screen to identify biologically active molecules for library production, design a library for approaching a biological target, determine the drug likeness of the proposed library using computational tools, develop synthetic strategies for their proposed libraries using solution or solid phase rapid parallel synthesis (RPS) and other library synthesis techniques, develop purification strategies for the proposed libraries and propose new reactions, reagents and technologies for library production.


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